Cyclosporine A as a Primary Treatment for Panniculitis-like T Cell Lymphoma: A Case with a Long-Term Remission

نویسندگان

  • Won Sup Lee
  • Ji-Hyen Hwang
  • Moon Jin Kim
  • Se-Il Go
  • Anna Lee
  • Haa-Na Song
  • Min Jeong Lee
  • Myung Hee Kang
  • Hoon-Gu Kim
  • Jeong-Hee Lee
چکیده

Subcutaneous panniculitis-like T cell lymphoma (SPTL) is a distinctive cutaneous lymphoma characterized by an infiltration of subcutaneous tissue by neoplastic T cells, similar to panniculitis. It is well-established that patients who are diagnosed with SPTL usually respond poorly to chemotherapy, showing fatal outcome. As a first line treatment for SPTL, anthracycline-based chemotherapy was most frequently used. For the treatment of SPTL, the efficacy of cyclosporine A has been recently reported in relapsed SPTL after anthracycline-based chemotherapy. However, it is still not clear whether cyclosporine A can be used as a first-line treatment against SPTL. Here, we report a case of SPTL, which achieved complete remission for nine years after first-line cyclosporine A therapy. This study suggests that cyclosporine A can induce a complete long-term remission as a first-line treatment.

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عنوان ژورنال:

دوره 46  شماره 

صفحات  -

تاریخ انتشار 2014